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US Brand: CeeNU
Indian (Generic) Brand: Medustine
Manufacturing: Medicon Pharma
Active Substance: Lomustine
Dosage: 40mg
Form release: Blister of 10 Capsules
Availability / Pricing: through enquiry form
Shipping time: 9 – 14 days

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Description

Lomustine – alkylating anticancer drug action from the group nitrosoureas. The mechanism of action consists in the alkylation of DNA and RNA. Inhibition of DNA synthesis caused by carbamoylation DNA polymerase and other DNA repair enzymes, and damage the DNA template.

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US Brand: Bonviva / Boniva / Bondronat
Indian (Generic) Brand: Bandrone / Idrofos
Manufacturing: Natco Pharma / Sun Pharma
Active Substance: Ibandronic Acid
Dosage: 150mg
Form release: Blister 1 tablet / 4 tablets
Availability / Pricing: through enquiry form
Shipping time: 9 – 14 days

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Description

Ibandronic acid (ibandronate sodium), – means for inhibiting bone resorption. Regulates blood calcium and the bone tissue, specifically inhibits increased bone resorption by osteoclasts. Used in hypercalcemia of tumor (cancer of the lungs, kidneys, urinary tract and other malignancies), hypercalcemia due to the destruction of the bone (paraproteinemic hematological malignancies, lymphomas, bone metastases in breast cancer, some solid cancers), postmenopausal osteoporosis (to prevent fractures).

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US Brand: Arimidex
Indian (Generic) Brand: Anabrez / Armotraz
Manufacturing: Sun Pharma / Cipla
Active Substance: Anastrozole
Dosage: 1mg
Form release: Blister 5 tablets / 10 tablets
Availability / Pricing: through enquiry form
Shipping time: 9 – 14 days

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Description

Is active against estrogen-breast tumors in women in the postmenopausal period. Androstenedione – main source of circulating estrogen in postmenopausal women, in peripheral tissues is converted into estrone, estradiol and then, this process occurs by the enzyme aromatase.

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US Brand: Deltasone
Indian (Generic) Brand: OMNACORTIL
Manufacturing: MACLEODS
Active Substance: Prednisolone
Dosage: 5mg / 10mg / 20mg / 40mg
Form release: blister 10 tabs
Order: through enquiry form
Shipping time: 9 – 14 days

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Description

Hormonal ( glucocorticoid for systemic and topical use ) . Is dehydrogenated analogue of hydrocortisone .

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US Brand: Nolvadex
Indian (Generic) Brand: Tamilong
Manufacturing: HAB
Active Substance: Tamoxifen
Dosage: 20mg
Form release: blister 10 tabs
Order: through enquiry form
Shipping time: 9 – 14 days

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Description

Twofold increase in the duration of tamoxifen daily dosing, with five to ten years, reduces mortality and the risk of recurrence in patients with estrogen-dependent breast cancer, particularly during the next decade after discontinuation of the drug.

These are the results of a long-term study conducted by an international team of scientists, which included experts from the UK, France, India, Argentina, Brazil, Egypt, Spain, Australia, Iran, China, Israel, Poland, Chile, Italy, the Czech Republic and Oman. The work is published in the journal The Lancet.

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US Brand: Clomid
Indian (Generic) Brand: Fertyl
Manufacturing: Any
Active Substance: Clomiphene
Dosage: 25mg / 50mg / 100mg
Form release: blister 10 tabs
Order: through enquiry form
Shipping time: 9 – 14 days

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Description

Binds estrogen receptors in the hypothalamus and ovaries. If ingestion is well absorbed from the gastrointestinal tract. Metabolized in the liver. Excreted in the bile and undergoes enterohepatic recycling. From the body is excreted in the feces. T1 / 2 of 5-7 days. In small doses, increases the secretion of gonadotropins (prolactin, FSH and LH) stimulates ovulation. At low levels of endogenous estrogen in the body has a mild estrogenic effect, at a high level – antiestrogen. Reducing the level of circulating estrogen promotes the secretion of gonadotropins. In high doses, inhibits the secretion of gonadotropins. Progestogenic and androgenic activity is not.

US Brand: Phenegran
Indian (Generic) Brand: AVOMINE / AVOCEN
Manufacturing: Any
Active Substance: Promethazine
Dosage: 25mg
Form release: blister 10 tabs
Order: through enquiry form
Shipping time: 9 – 14 days

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Description

The most important pharmacological diprazina feature is its strong antihistamines (H1-blocking) activity. Promethazine is well absorbed when taken orally. For different routes of administration penetrates the blood-brain barrier. The drug has a pronounced effect on the central nervous system; has a fairly strong sedative activity, enhances the effect of drugs, hypnotics, analgesics and local anesthetics, lowers body temperature, prevents and calms vomiting. He also has a moderate peripheral and central holinoliticheskoe effect. Strongly expressed adrenoliticheskoe effect diprazina.

US Brand: ANDRIOL
Indian (Generic) Brand: CERNOS CAP
Manufacturing: Sun Pharma
Active Substance: Testosterone Undecanoate
Dosage: 40mg
Form release: blister 10 capsules
Order: through enquiry form
Shipping time: 9 – 14 days

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Studies have shown that testosterone undecanoate has no toxic effect on the liver as the suction from the digestive tract it enters into the lymph (rather than into the bloodstream), wherein a current through the common lymphatic duct enters the general circulatory system, therefore bypasses the liver. In the body, undecanoate converted into dihydrotestosterone – the active metabolite of testosterone, that is, in fact, the substance is a prohormone.

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US Brand: ANDRIOL
Indian (Generic) Brand: ANDRIOL
Manufacturing: ORGANON
Active Substance: Testosterone Undeconoate
Dosage: 40mg
Form release: blister 10 capsules
Order: through enquiry form
Shipping time: 9 – 14 days

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Fills deficit of endogenous testosterone. Regulates protein, nitrogen, phosphorus metabolism, stimulates the development of male sex organs and secondary sexual characteristics.

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US Brand: ANDROGEL
Indian (Generic) Brand: CERNOS GEL
Manufacturing: Sun Pharma
Active Substance: Testosterone USP
Dosage: 1%
Form release: 1 sachet 5 gramm, or 50mg of Testosterone USP
Order: through enquiry form
Shipping time: 9 – 14 days

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Pharmacodynamics

Endogenous androgens secreted by the testes (mainly testosterone) and their main metabolite dihydrotestosterone responsible for the development of external and internal genital organs and for maintaining secondary sex characteristics (stimulating hair growth, deepening of the voice, the development of the libido); for the overall impact on the anabolism of proteins; for the development of the skeletal muscles and the distribution of subcutaneous fat; for reducing the excretion of nitrogen, sodium, potassium, chloride, phosphate, and water. Testosterone does not cause testicular development: it reduces the secretion of pituitary gonadotropins.
Effects of testosterone on some target organs is manifested after peripheral conversion of testosterone to estradiol, which then binds to the estrogen receptor in the nuclei of target cells (such as the pituitary, adipose tissue, brain, bone, and testicular Leydig cells).

Indications for use

Replacement therapy with testosterone deficiency.

Dosing and Administration

The recommended dose of 5 grams of gel (i.e. 50 mg of testosterone), used 1 time per day at about the same time, preferably in the morning. Individual daily dose may be adjusted by the physician according to the clinical and laboratory data for patients but does not exceed 10 g of gel per day. Correction mode should be performed in steps of 2.5 g of gel per day.
The gel is applied to clean, dry, intact skin shoulders, arms and / or abdomen. After opening the bag should be immediately put on your skin and all of its contents spread a thin layer. Not necessarily rub it into the skin. Let it dry for at least 3-5 minutes before dressing. After applying the gel, wash your hands with soap and water.
Do not apply the gel to the genital area, because the high ethanol content in the preparation may cause local irritation.
Constant concentration of testosterone in plasma is approximately on the second day of treatment AndroGel. For adjustment of the dosage necessary to determine the concentration of testosterone in serum testosterone in the morning before application of the drug from the third day after treatment (within one week). The dosage can be reduced if the content of testosterone in the plasma was increased. If low concentrations, the dose can be increased, but not more than 10 g of gel per day.

More information at:

http://www.fda.gov/downloads/Drugs/DrugSafety/UCM294248.pdf