US Brand: PLATINOL
Indian (Generic) Brand: Cytoplatin
Manufacturing: Cipla
Active Substance: Cisplatin
Dosage: 50mg/50ml
Form release: bottle (aqueous)
Shipping time: 9 – 14 days

Description

The mechanism of action is similar to the action of other alkylating agents and is in violation of the functions of DNA, cause chemical damage to DNA bases. Chemical DNA damage (“platinum adduct”) is formed by forming a coordination bond between the platinum atom and two DNA bases (preferably guanine), resulting in DNA form intra- and interstrand crosslinks. At the cellular level, cisplatin causes a disturbance of replication and transcription, leading to cell cycle arrest and apoptosis.

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