US Brand: Temodal / Temodar
Indian (Generic) Brand: Temonat
Manufacturing: Cipla / Natco
Active Substance: Temozolomide
Dosage: 250mg / 100mg
Form release: bottle 5 cabs
Shipping time: 9 – 14 days
Description
Pharmacological action – an antineoplastic alkylating, immunosuppressive. In the systemic circulation at physiological pH values undergoes rapid chemical conversion in the cytotoxic monometiltriazenoimidazolkarboksamid (MTIK). MTIK cytotoxic effect caused by alkylation of guanine at position O6 and N7 (optional), followed by the launch of aberrant recovery methyl residue. Penalized structure and DNA synthesis, cell cycle.